Baloxavir Marboxil 1985606-14-1
Ka hope
ʻO Baloxavir marboxil kahi lāʻau antiviral a he mea hoʻopaneʻe endonuclease.I nā ʻiole a me nā monkey, ʻoi aku ka haʻahaʻa o ke koko o ka lāʻau lapaʻau ma mua o ka liʻiliʻi liʻiliʻi i ʻike ʻia i ka hoʻokele waha o ka lāʻau.I loko o nā ʻano maʻi maʻi maʻi preclinical A a me B (me nā maʻi e kū nei i nā lāʻau antiviral e kū nei), he hopena ko Baloxavir marboxil.
Na Waiwai Kemika
| Waihona | E mālama i ka -20°C |
| M.Wt | 571.55 |
| Cas No. | 1985606-14-1 |
| Kumukumu | C27H23F2N3O7S |
| Nā huaʻōlelo like | S-033188 |
| Solubility | Hiki ke hoʻoheheʻe ʻia ma DMSO |
| Inoa Kimia | (((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate |
| SDF | Hoʻoiho iā SDF |
| KANAKA MAKANA | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O |
| Kūlana moku | Haʻina hāpana loiloi: moku me ka hau polū.Loaʻa nā nui ʻē aʻe: moku me RT, a i ʻole hau polū ma ke noi. |
| Nā ʻōlelo aʻoaʻo maʻamau | No ka loaʻa ʻana o ka solubility kiʻekiʻe, e ʻoluʻolu e hoʻomehana i ka paipu ma 37 ° C a lulu i loko o ka ʻauʻau ultrasonic no kekahi manawa.Hiki ke mālama ʻia ka hoʻonā waiwai ma lalo o -20°C no kekahi mau mahina. |
ʻO ke kinona
Manaʻo18Nā papahana Loiloi Kūlike Kūlike i ʻae ʻia4, a6nā papahana ma lalo o ka ʻae ʻia.
Ua hoʻokumu ka ʻōnaehana hoʻokele maikaʻi honua kiʻekiʻe i ke kumu kūʻai.
Holo ka nānā ʻana i ka maikaʻi ma ke ola holoʻokoʻa o ka huahana e hōʻoia i ka maikaʻi a me ka hopena therapeutic.
Kākoʻo ka hui ʻoihana Regulatory Affairs i nā koi maikaʻi i ka wā o ke noi a me ke kau inoa ʻana.
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