Hoʻohana ʻia ʻo Relugolix e mālama i ka maʻi prostate i nā kāne.
Nā inoa inoa: Orgovyx
Papa Laau Laau: Antineoplastic - LHRH (GnRH) Antagonist Pituitary Suppressants
Loaʻa: Pono ka ʻōlelo kuhikuhi
Hāpai: E nīnau i kāu kauka. Hiki ke pilikia kēia lāʻau i ke keiki hānau ʻole.
Lactation: E nīnau i ke kauka ma mua o ka hoʻohana ʻana

ʻO Relugolix kahi mea kūʻē waha, non-peptide gonadotropin-releasing hormone (GnRH a i ʻole luteinizing hormone-releasing hormone (LHRH)) antagonist, me ka hana antineoplastic. Hoʻopaʻa hoʻokūkū ʻo Relugolix a hoʻopaʻa i ka mea loaʻa GnRH i ka pituitary gland anterior, ka mea e pale ai i ka GnRH e hoʻopaʻa i ka mea hoʻokipa GnRH a pale i ka huna a me ka hoʻokuʻu ʻana o ka hormone luteinizing (LH) a me ka follicle stimulating hormone (FSH). I nā kāne, ʻo ka pale ʻana i ka huna ʻana o LH e pale i ka hoʻokuʻu ʻana o ka testosterone mai nā cell Leydig i loko o nā hōʻike. No ka mea e koi ʻia ka testosterone e hoʻomau i ka ulu ʻana o ka prostate, ʻo ka hōʻemi ʻana i nā pae testosterone hiki ke pale i ka hoʻonui ʻia ʻana o ka maʻi kanesa prostate.

ʻO Relugolix kahi mea hoʻokuʻu gonadotropin-releasing hormone (GnRH) receptor antagonist i hoʻohana ʻia i ka mālama ʻana i kekahi mau kūlana e pane ai i ka hormone. Ua ʻae mua ʻia ma Iapana i ka makahiki 2019, ma lalo o ka inoa inoa Relumina, no ka mālama ʻana i ka maʻi maʻi o ka fibroids uterine, a i kēia manawa hou e ka United States 'FDA ma 2020, ma lalo o ka inoa inoa Orgovyx, no ka mālama ʻana i ka maʻi maʻi prostate holomua. Ua aʻo pū ʻia ʻo Relugolix i ka mālama ʻana i ka endometriosis. ʻO Relugolix ka mua (a i kēia manawa wale nō) i hāʻawi ʻia i ka waha i ka GnRH receptor antagonist i ʻae ʻia no ka mālama ʻana i ka maʻi maʻi prostate - nā ʻano lapaʻau like e like me [degarelix] e koi i ka hoʻokele subcutaneous - a no laila hāʻawi i kahi koho therapeutic haʻahaʻa haʻahaʻa no nā poʻe maʻi e koi aku i nā kipa keʻena. no ka hooponopono ana e ka poe oihana ola kino. Ma waho aʻe o kona maʻalahi o ka hoʻohana ʻana, ua hōʻike ʻia ʻo relugolix i ke kiʻekiʻe o ke kaumaha o nā pae testosterone ke hoʻohālikelike ʻia me [leuprolide], kahi lāʻau lapaʻau androgen deprivation i hoʻohana ʻia i ka mālama ʻana i ka maʻi maʻi prostate.

ʻO Relugolix kahi Gonadotropin Hoʻokuʻu i ka Hormone Receptor Antagonist. ʻO ke ʻano o ka hana o ka relugolix e like me kahi Gonadotropin Releasing Hormone Receptor Antagonist, a me Cytochrome P450 3A Inducer, a me Cytochrome P450 2B6 Inducer, a me ka Breast Cancer Resistance Protein Inhibitor, a me P-Glycoprotein Inhibitor. ʻO ka hopena physiologic o ka relugolix ma o ka hoʻohaʻahaʻa ʻana i ka huna huna GnRH.

ʻO ke kinona