Relugolix 737789-87-6

ʻO ka wehewehe pōkole:

Ka inoa o ka API Hōʻike Hōʻike US DMF EU DMF CEP
Ribociclib CAS: 737789-87-6 Atineoplastic I-Hale      


Huahana Huahana

Huahana Huahana

NUI HUA

Hoʻohana ʻia ʻo Relugolix e mālama i ka maʻi prostate i nā kāne.
Nā inoa inoa: Orgovyx
Papa Laau Laau: Antineoplastic - LHRH (GnRH) Antagonist Pituitary Suppressants
Loaʻa: Pono ka ʻōlelo kuhikuhi
Hāpai: E nīnau i kāu kauka.Hiki ke pilikia kēia lāʻau i ke keiki hānau ʻole.
Lactation: E nīnau i ke kauka ma mua o ka hoʻohana ʻana

ʻO Relugolix kahi mea kūʻē waha, non-peptide gonadotropin-releasing hormone (GnRH a i ʻole luteinizing hormone-releasing hormone (LHRH)) antagonist, me ka hana antineoplastic.Hoʻopaʻa hoʻokūkū ʻo Relugolix a hoʻopaʻa i ka mea loaʻa GnRH i ka pituitary gland anterior, ka mea e pale ai i ka hoʻopaʻa ʻana o GnRH i ka mea hoʻokipa GnRH a keʻakeʻa i ka huna a me ka hoʻokuʻu ʻana o ka hormone luteinizing (LH) a me ka follicle stimulating hormone (FSH).I nā kāne, ʻo ka pale ʻana i ka huna ʻana o LH e pale i ka hoʻokuʻu ʻana o ka testosterone mai nā pūnaewele Leydig i loko o nā hōʻike.No ka mea e koi ʻia ka testosterone e hoʻomau i ka ulu ʻana o ka prostate, ʻo ka hōʻemi ʻana i nā pae testosterone hiki ke kāohi i ka hoʻonui ʻana o ka maʻi maʻi maʻi maʻi prostate.

ʻO Relugolix kahi mea hoʻokuʻu gonadotropin-releasing hormone (GnRH) receptor antagonist i hoʻohana ʻia i ka mālama ʻana i kekahi mau kūlana e pane ai i ka hormone.Ua ʻae mua ʻia ma Iapana i ka makahiki 2019, ma lalo o ka inoa inoa Relumina, no ka mālama ʻana i ka maʻi maʻi o ka fibroids uterine, a ʻoi hou aʻe e ka United States 'FDA ma 2020, ma lalo o ka inoa inoa ʻo Orgovyx, no ka mālama ʻana i ka maʻi maʻi prostate holomua.Ua aʻo pū ʻia ʻo Relugolix i ka mālama hōʻailona o ka endometriosis.ʻO Relugolix ka mua (a i kēia manawa wale nō) i hāʻawi ʻia i ka waha i ka GnRH receptor antagonist i ʻae ʻia no ka mālama ʻana i ka maʻi maʻi prostate - nā ʻano lapaʻau like e like me [degarelix] koi i ka hoʻokele subcutaneous - a no laila hāʻawi i kahi koho therapeutic haʻahaʻa kaumaha no nā poʻe maʻi e koi aku i nā kipa keʻena. no ka hooponopono ana e ka poe oihana ola kino.Ma waho aʻe o kona maʻalahi o ka hoʻohana ʻana, ua hōʻike ʻia ʻo relugolix i ke ʻano o ke kaumaha o nā pae testosterone ke hoʻohālikelike ʻia me [leuprolide], kahi lāʻau hoʻopau androgen i hoʻohana ʻia i ka mālama ʻana i ka maʻi maʻi prostate.

ʻO Relugolix kahi Gonadotropin Hoʻokuʻu i ka Hormone Receptor Antagonist.ʻO ke ʻano o ka hana o ka relugolix e like me kahi Gonadotropin Releasing Hormone Receptor Antagonist, a me Cytochrome P450 3A Inducer, a me Cytochrome P450 2B6 Inducer, a me ka Breast Cancer Resistance Protein Inhibitor, a me P-Glycoprotein Inhibitor.ʻO ka hopena physiologic o ka relugolix ma o ka hoʻohaʻahaʻa ʻana i ka huna huna GnRH.

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