Chlorothiazide

Hōʻike Pōkole:

Ka inoa o API Hōʻike Hoakaka US DMF  EU DMF  CEP
Chlorothiazide ʻO Diuretics USP / EP      

ʻIke kikoʻī

Nā huahana huahana

ʻIkepili Huahana

Papa kāʻei kua

He mea kāohi ʻo Chlorothiazide i ka anhydrase kalapona a ʻoi aku ka liʻiliʻi o ka ikaika ma mua o ka acetazolamide. Ua hōʻike ʻia kēia hui e ālai i ka reabsorption o nā iona sodium a me chloride.

Wehewehe

ʻO Chlorothiazide kahi diuretic a me antihypertensive. (IC50 = 3.8 mM) Pahuhopu: ʻO kekahi Chlorothiazide sodium (Diuril) kahi diuretic i hoʻohana ʻia i loko o ka haukapila hoʻonohonoho a i ʻole no ka hoʻohana pilikino ʻana e hoʻokele i ka nui o ka wai e pili ana me ka puʻuwai puʻuwai congestive. Hoʻohana ʻia ia ma ke ʻano he antihypertensive. Lawe pinepine ʻia i ka pila pila, lawe pinepine ʻia ia ma ka waha hoʻokahi a i ʻole ʻelua mau manawa i ka lā. I ka hoʻonohonoho ICU, hāʻawi ʻia ʻo chlorothiazide i diurese kahi mea maʻi ma ka hoʻohui o ka furosemide (Lasix). Ke hana nei i kahi ʻano kaʻawale ma mua o ka furosemide, a komo ʻoluʻolu e like me kahi hoʻomaha hoʻomaha i lawelawe ʻia ma o ka tube nasogastric (NG tube), hiki i nā lāʻau ʻelua ke hoʻoikaika i kekahi i kekahi.

Hoʻokolohua Lapaʻau

Helu NCT Kākoʻo Kūlana Lā Hoʻomaka

ʻĀpana

NCT03574857 Kulanui o Virginia Ka Puʻuwai puʻuwai | Hōʻeha puʻuwai me ka hoʻoliʻiliʻi hoʻoliʻiliʻi | ʻO ka puʻuwai puʻuwai Iune 2018

Pae 4

NCT02546583 Ke Kulanuiʻo Yale | National Heart, Lung, a me Blood Institute (NHLBI) Hoka Puʻuwai ʻAukake 2015

Pili 'ole

NCT02606253 Kula Nui Vanderbilt | Hale Waihona Lapaʻau Kula ʻo Vanderbilt Hoka Puʻuwai Pepeluali 2016

Pae 4

NCT00004360 National Center for Research Resources (NCRR) | Ke Kulanui o Northwestern | Office of Rare Diseases (ORD) ʻO Diabetes Insipidus, nephrogenic Kepakemapa 1995

NCT00000484 National Heart, Lung, and Blood Institute (NHLBI) Nā maʻi maʻi puʻuwai | Nā maʻi puʻuwai | Hypertension | Nā maʻi Vascular ʻApelila 1966

Kau 3

ʻAno kemika

Chlorothiazide

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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