Ma Sepatemaba 27, ua ʻae ʻia ka palapala noi no ka hōʻailona hou o Pfize Crisaborole cream (inoa kālepa Kina: Sultanming, inoa kālepa Pelekane: Eucris a, Staquis) i ʻae ʻia, no nā keiki a me nā pākeke ʻo 3 mau mahina a nā maʻi dermatitis atopic kahiko.

ʻO Crisaborole kahi mole liʻiliʻi, non-hormonal, nonsteroidal anti-inflammatory topical phosphodiesterase 4 (PDE-4) inhibitor i hoʻomohala ʻia e Anacor.I Mei 2016, ua loaʻa iā Pfizer ka hui no $5.2 biliona a loaʻa ka lāʻau lapaʻau.I Kekemapa o ia makahiki, ua ʻae ʻia ʻo Crisaborole e ka FDA no ke kūʻai ʻana, e lilo ana i lāʻau lapaʻau mua no ka dermatitis atopic i ʻae ʻia i loko o 10 mau makahiki, a ʻo ka lāʻau lapaʻau mua nonsteroidal waho e kāohi i ka ʻili PDE4.

ʻO Crisaborole Inhibitors ma ke ʻano he lāʻau lapaʻau hou, ʻoiaʻiʻo, ua hoʻohana ʻia nā ʻano o ka waha no ka psoriasis plaque maʻamau a me ka psoriatic arthritis, ʻo ka hopena koʻikoʻi ka pilikia o ka ʻōpū, ʻaʻohe mea ʻē aʻe.

ʻO Crisaborole e like me nā lāʻau lapaʻau Topical, ʻaʻole i komo i loko o ka ʻili, hoʻemi ʻia ka hopena o kēia hopena ʻaoʻao o ka ʻeha o ka ʻōpū i kahi haʻahaʻa loa.

ʻO ka hopena, ua lilo koke ʻo Crisaborole i "manaolana o ke kauhale holoʻokoʻa" mai 15 mau makahiki, ua makemake nui nā kauka a me nā mākua e loaʻa kahi palekana, maikaʻi a lōʻihi hoʻi ka hoʻohana ʻana i nā lāʻau lapaʻau.

Pehea ka maikaʻi o ka lāʻau me Crisaborole?

Ma 2016, ʻelua mau haʻawina hoʻokolohua hoʻokolohua Phase III i lawe mai i nā nūhou hoihoi loa, ʻo Crisaborole, kahi ʻaila poni o phosphodiesterase-4 (PDE4) inhibitors, no nā mea maʻi me ka dermatitis atopic ma mua o 2 mau makahiki (keiki a me nā mākua), ua loaʻa nā hopena lapaʻau maikaʻi.