Enalapril Maleate
Ka hope
Enalapril Maleate
wehewehe
ʻO Enalapril (maleate) (MK-421 (maleate)), ka metabolite ikaika o ka enalapril, he mea hoʻohiolo i ka angiotensin-converting enzyme (ACE).
Ma Vivo
ʻO ka Enalapril (MK-421) kahi prodrug i pili i ka papa o nā lāʻau lapaʻau angiotensin-converting enzyme (ACE).Hoʻopili koke ia i loko o ke ake i ka enalaprilat ma hope o ka hoʻohana waha.ʻO Enalapril (MK-421) kahi mea hoʻokūkū ikaika, hoʻokūkū hoʻokūkū o ACE, ka enzyme kuleana no ka hoʻololi ʻana o ka angiotensin I (ATI) i ka angiotensin II (ATII).Hoʻoponopono ʻo ATII i ke koko a he mea nui ia o ka renin-angiotensin-aldosterone system (RAAS).Hiki ke hoʻohana ʻia ʻo Enalapril e mālama i ka hypertension koʻikoʻi a i ʻole renovascular a me nā hōʻailona congestive heart failure.
Waihona
| Pauda | -20°C | 3 makahiki |
| 4°C | 2 makahiki | |
| I ka solvent | -80°C | 6 mahina |
| -20°C | 1 mahina |
ʻO ke kinona
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