Hoʻohana ʻia kēia lāʻau lapaʻau e nā wahine e kōkua i ka hoʻomaha ʻana i ka ʻeha haʻahaʻa a koʻikoʻi ma muli o kahi maʻi i kapa ʻia ʻo endometriosis.
Hiki ke mālama: Endometriosis
Nā inoa inoa: Orilissa
Papa Laau Laau: LHRH (GnRH) Antagonists
Loaʻa: Pono ka ʻōlelo kuhikuhi
Hāpai: E hōʻalo i ka hoʻohana ʻana i ka wā hāpai
Lactation: E nīnau i ke kauka ma mua o ka hoʻohana ʻana

ʻO Elagolix kahi mea olaola waha, lua-hanauna, non-peptide i hoʻokumu ʻia, pūhui mole liʻiliʻi a me ka gonadotropin-releasing hormone (GnRH; LHRH) receptor antagonist, me ka hana hoʻoneʻe ʻana i ka hormone. Ma ka hoʻoponopono waha, hoʻokūkū ʻo elagolix me GnRH no ka hoʻopaʻa ʻana i ka mea hoʻopaʻa a hoʻopaʻa i ka hōʻailona hōʻailona GnRH i ka pituitary gland anterior. Mālama kēia i ka huna ʻana o ka hormone luteinizing (LH) a me ka follicle stimulating hormone (FSH). I nā kāne, ʻo ka pale ʻana i ka huna LH e pale i ka hoʻokuʻu ʻana o ka testosterone. I nā wahine, ʻo ka pale ʻana i ka FSH a me LH e pale i ka hana ʻana o ka estrogen e nā ovaries. Hiki ke mālama a pale paha i nā hōʻailona o nā maʻi pili i ka hormone sex.

ʻO Elagolix kahi mea kū'ē waha, nonsteroidal gonadotropin hoʻokuʻu i ka hormone (GnRH) e hoʻemi ana i ka hana estrogen a hoʻohana ʻia e mālama i nā ʻano ʻeha o ka endometriosis i nā wahine. Hoʻopili ʻia ka lāʻau ʻo Elagolix me ka haʻahaʻa haʻahaʻa o ka piʻi ʻana o ka enzyme serum i ka wā o ka lāʻau lapaʻau a ʻaʻole naʻe i hoʻopili ʻia i nā manawa o ka hōʻeha ate.

Ua hoʻohana ʻia ʻo Elagolix i nā hoʻokolohua e aʻo ana i ka ʻepekema kumu a me ka mālama ʻana o Endometriosis, Folliculogenesis, Uterine Fibroids, Heavy Uterine Bleeding, a me Heavy Menstrual Bleeding. Ma ka 24 Iulai 2018, akā naʻe, ua ʻae ka US Food and Drug Administration (FDA) i ka elagolix o AbbVie ma lalo o ka inoa inoa ʻo Orilissa ma ke ʻano he mea kūʻē mua a me ka waha gonadotropin-releasing hormone (GnRH) antagonist i kūkulu pono ʻia no nā wahine me ka ʻeha endometriosis haʻahaʻa a koʻikoʻi. Ua hoʻoholo ʻia ʻo ka endometriosis kekahi o nā maʻi gynecologic maʻamau ma ʻAmelika Hui Pū ʻIa. ʻO ka mea nui, hōʻike nā manaʻo hoʻokahi i loko o nā wahine he ʻumi o ka makahiki hānau e hoʻopilikia ʻia e ka endometriosis a ʻike i nā hōʻailona hōʻeha ʻeha. Eia kekahi, hiki i nā wahine i loaʻa i kēia maʻi ke pilikia a hiki i ʻeono a ʻumi mau makahiki a kipa aku i nā kauka he nui ma mua o ka loaʻa ʻana o kahi hōʻailona kūpono. Ma hope mai, ʻoiai ua ʻae ʻia ʻo Orilissa (elagolix) e ka FDA ma lalo o ka loiloi mua, ua hāʻawi kēia ʻae wikiwiki hou i nā limahana mālama ola i kahi koho waiwai ʻē aʻe no ka mālama ʻana i nā pono kūpono ʻole o nā wahine i hoʻopilikia ʻia e ka endometriosis, ma muli o ko lākou ʻano kikoʻī a me ka paʻakikī o ka ʻeha endometriosis. .

ʻO ke kinona