Crisaborole
He lālā ʻo Crisaborole o ka papa o benzoxaboroles ʻo ia ka 5-hydroxy-1,3-dihydro-2,1-benzoxaborole kahi i loaʻa ai ka phenolic.hydrogenua pani ʻia e kahi hui 4-cyanophenyl. He phosphodiesterase 4 inhibitor i hoʻohana ʻia no ka mālama ʻana i ka dermatitis atopic haʻahaʻa i nā keiki a me nā pākeke. He kuleana kona ma ke ʻano he phosphodiesterase IV inhibitor, aantisoriatica me ka lāʻau anti-inflammatory non-steroidal. He benzoxaborole ia, he ether aromatic a me ka nitrile.
He puke moʻolelo ʻo Crisaboroleoxaborolei ʻae ʻia e FDA ma Dekemaba 14, 2016 e like me Eucrisa, kahi lāʻau lapaʻau no ka dermatitis atopic maʻalahi a maʻalahi. He mea maikaʻi kēia mea hana non-steroidal i ka hoʻomaikaʻi ʻana i ka paʻakikī o ka maʻi, e hōʻemi i ka hopena o ka maʻi a me ka hōʻemi ʻana i nā hōʻailona a me nā hōʻailona i nā maʻi 2 mau makahiki a keu. Hoʻemi ia i ka mumū kūloko i ka ʻili a pale i ka exacerbation hou o ka maʻi me kahi kūlana palekana maikaʻi. Aia i loko o kona hale aboronaatom, ka mea e hoʻomaʻamaʻa i ke komo ʻana o ka ʻili a hoʻopaʻa i ke kikowaena bimetal o ka phosphodiesterase 4 enzyme. Ke kūkulu ʻia nei ia ma ke ʻano he lāʻau lapaʻau o psoriasis.
ʻO Crisaborole kahi mea pale Phosphodiesterase 4. ʻO ke ʻano o ka hana o ka crisaborole ma ke ʻano he Phosphodiesterase 4 Inhibitor.





Manaʻo18Nā papahana Loiloi Kūlike Kūlike i ʻae ʻia4, a6apono ʻia nā papahana.

Ua hoʻokumu ka ʻōnaehana hoʻokele maikaʻi honua kiʻekiʻe i ke kumu kūʻai.

Holo ka nānā ʻana i ka maikaʻi ma ke ola holoʻokoʻa o ka huahana e hōʻoia i ka maikaʻi a me ka hopena therapeutic.

Kākoʻo ka hui ʻoihana Regulatory Affairs i nā koi maikaʻi i ka wā o ke noi a me ke kākau inoa ʻana.


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