Crisaborole
ʻO Crisaborole kahi lālā o ka papa o benzoxaboroles ʻo ia ka 5-hydroxy-1,3-dihydro-2,1-benzoxaborole kahi i loaʻa ai ka phenolic.hydrogenua pani ʻia e kahi hui 4-cyanophenyl.He phosphodiesterase 4 inhibitor i hoʻohana ʻia no ka mālama ʻana i ka dermatitis atopic haʻahaʻa i nā keiki a me nā pākeke.He kuleana kona ma ke ʻano he phosphodiesterase IV inhibitor, aantisoriatica me kahi lāʻau anti-inflammatory non-steroidal.He benzoxaborole ia, he ether aromatic a me ka nitrile.
He moʻolelo ʻo Crisaboroleoxaborolei ʻae ʻia e FDA ma Dekemaba 14, 2016 e like me Eucrisa, kahi lāʻau lapaʻau no ka dermatitis atopic maʻalahi a maʻalahi.He mea maikaʻi kēia mea non-steroidal i ka hoʻomaikaʻi ʻana i ka nui o ka maʻi, e hōʻemi i ka hopena o ka maʻi a me ka hōʻemi ʻana i nā hōʻailona a me nā hōʻailona i nā maʻi 2 mau makahiki a keu.Hoʻemi ia i ka mumū kūloko i loko o ka ʻili a pale i ka exacerbation hou o ka maʻi me kahi kūlana palekana maikaʻi.Aia i loko o kona hale aboronaatom, ka mea e hoʻomaʻamaʻa i ke komo ʻana o ka ʻili a hoʻopaʻa i ke kikowaena bimetal o ka phosphodiesterase 4 enzyme.Ke kūkulu ʻia nei ia ma ke ʻano he lāʻau lapaʻau o psoriasis.
ʻO Crisaborole kahi mea pale Phosphodiesterase 4.ʻO ke ʻano o ka hana o ka crisaborole ma ke ʻano he Phosphodiesterase 4 Inhibitor.
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