Abrocitinib

ʻO ka wehewehe pōkole:

Ka inoa o ka API Hōʻike Mea hana hou Lā Hoʻopau Patent (ʻAmelika)
Abrocitinib ʻO ka Dermatitis Atopic Pfizer Feb.11, 2034


Huahana Huahana

Huahana Huahana

NUI HUA

ʻO Abrocitinib kahi mole waha, liʻiliʻi liʻiliʻi, Janus kinase (JAK) 1 inhibitor i ka hoʻomohala ʻana no ka mālama ʻana i nā poʻe mākua a me nā ʻōpio me ke ʻano o ka dermatitis atopic koʻikoʻi.

Ke hoʻokolokolo ʻia nei ʻo Abrocitinib i ka hoʻokolohua lapaʻau NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy i nā ʻōpio me ka Dermatitis Atopic).

Ke kūkulu ʻia nei ʻo Abrocitinib e Pfizer no ka mālama ʻana i ka dermatitis atopic (eczema).He mea hoʻopaneʻe waha ʻo Janus kinase 1 (JAK1) i hoʻokahi lā.

ʻO ka dermatitis atopic (AD) he maʻi paʻakikī, maʻi, a me ka maʻi ʻili i hōʻike ʻia e ka pruritic, ka ʻiʻo nui, a me nā ʻeha eczematous e pili ana i ka 25% o nā keiki a me 2% a 3% o nā pākeke ma ka honua holoʻokoʻa.ʻO Abrocitinib kahi mea paʻa koho o Janus kinase-1 (JAK1) enzyme e kāohi ana i ke kaʻina hana inflammatory.No laila, ua manaʻo mākou e loiloi i ka maikaʻi a me ka palekana o ka abrocitinib no AD haʻahaʻa a koʻikoʻi.

ʻO ka Abrocitinib i ka dose 100 mg a i ʻole 200 mg he lāʻau lapaʻau maikaʻi, ʻae ʻia, a hoʻohiki i ka mālama ʻana i nā poʻe maʻi me ka dermatitis atopic haʻahaʻa a koʻikoʻi.Eia naʻe, ua makemake ka loiloi i ka maikaʻi o ka abrocitinib 200 mg ma luna o 100 mg, akā ʻoi aku ka nui o nā hopena ʻaoʻao e like me ka nausea a me ke poʻo poʻo me ka 200 mg.

HOOLAHA ANOAI

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Holo ka nānā ʻana i ka maikaʻi ma ke ola holoʻokoʻa o ka huahana e hōʻoia i ka maikaʻi a me ka hopena therapeutic.

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