ʻO Ruxolitinib kahi ʻano o ka lāʻau lapaʻau waha i kapa ʻia he kinase inhibitor a hoʻohana nui ʻia e mālama i nā maʻi e like me ka maʻi graft-versus-host, erythroblastosis, a me ka myelofibrosis medium-a me kiʻekiʻe, aʻo Ruxolitinib cream he mea dermatological topical i hoʻohana ʻia. pololei ma ka ʻili e mālama i ka eczema, vitiligo, atopic dermatitis, a me ka ʻōhule. ʻOiai ʻokoʻa loa ʻo Ruxolitinib a me Ruxolitinib cream mai kekahi i kekahi, hiki ke huikau lākou no ka mea he inoa like ko lākou. ʻO Changzhou Pharmaceutical Factory (CPF), kahi alakaʻiMea hoʻolako Ruxolitinibma Kina, eia ke kālailai ʻana i nā ʻokoʻa ma waena o lākou ma ke ʻano o ʻekolu mau mea nui e kōkua iā ʻoe e ʻike hou aku e pili ana iā lākou.
1. Hōʻike
ʻO Ruxolitinibua ʻae ʻia e ka FDA i Nowemapa 2011 a e ka European Commission i ʻAukake 2012 a he ʻano lāʻau lapaʻau i kuhikuhi ʻia me nā hōʻailona maopopo. Hoʻohana ʻia ia no ka mālama ʻana i nā maʻi i loaʻa i ʻekolu ʻano maʻi, e like me ka maʻi steroid-refractory acute graft-versus-host maʻi, erythroblastosis, a me ka myelofibrosis pilikia (MF). Akā aia ʻo Ruxolitinib cream i ka pae hoʻomohala a hiki ʻole ke hele ma ka mākeke, no laila he lāʻau lapaʻau ia no ka mālama ʻana i ka maʻi shin a me ka ʻōhule a ʻaʻohe hōʻailona i ʻae ʻia. Eia naʻe, ua hōʻike nā haʻawina i ka maikaʻi o ka lāʻau lapaʻau o Ruxolitinib cream i ka mālama ʻana i ka vitiligo, atopic dermatitis a me ka ʻōhule koʻikoʻi.
2. Ke ala noi
ʻO Ruxolitinib kahi mea hoʻopaneʻe kinase waha e hana ana ma ke ʻano he mea hoʻopale mole liʻiliʻi o ka protein kinases JAK1 a me JAK2, a ʻo ia ka lāʻau lapaʻau mua i ʻae ʻia e ka FDA e mālama i ka myelofibrosis. Akā ʻo ka ʻaila Ruxolitinib he ʻaila hoʻohana topical e ʻokoʻa loa mai Ruxolitinib i ke ʻano o ka hoʻohana ʻana.
3. Ka hopena ʻaoʻao
Loaʻa iā Ruxolitinib nā hopena ʻaoʻao. ʻO nā hopena ʻaoʻao hematologic maʻamau e pili ana i kāna hoʻohana ʻana he hoʻemi ʻia ka helu platelet a me ka anemia, a ʻo nā hopena ʻaoʻao non-hematologic maʻamau ka petechiae, dizziness, a me ke poʻo. Eia nō naʻe, aia nō ka ʻaila Ruxolitinib i ka hoʻokolohua lapaʻau, no laila ʻaʻole i hoʻoholo ʻia kona hopena ʻaoʻao.
E hoʻokaʻaʻike iā CPF e kiʻi iā Ruxolitinib ma ke kumu kūʻai kūpono, a e hele i ka hoʻomaʻamaʻa hoʻokolohua hoʻokolohua e kiʻi i ka ʻaila Ruxolitinib no ka manuahi.
Ka manawa hoʻouna: Mei-12-2022