ʻO nā papa calcium Atorvastatin a me nā papa calcium rosuvastatin he mau lāʻau hoʻohaʻahaʻa lipid statin, a no nā lāʻau statin ikaika loa. ʻO nā ʻokoʻa kikoʻī penei:

1. Mai ka hiʻohiʻona o ka pharmacodynamics, inā like ka hopena, ʻoi aku ka ikaika o ka hopena hoʻohaʻahaʻa lipid o rosuvastatin ma mua o ka atorvastatin, akā no ka maʻi maʻamau i ʻōlelo ʻia e ka maʻi, ʻo ka hopena hoʻohaʻahaʻa lipid o nā lāʻau ʻelua he ʻano like. ;

2. Ma ke ʻano o ka lāʻau lapaʻau e pili ana i nā hōʻike, ʻoiai ʻo ka atorvastatin ma ka mākeke ma mua, ʻoi aku ka nui o nā hōʻike o ka atorvastatin i nā maʻi cardiovascular a me cerebrovascular ma mua o rosuvastatin; 3. Ma ke ʻano o ka metabolism lāʻau, aia kekahi ʻokoʻa ma waena o nā mea ʻelua. Hoʻopili nui ʻia ʻo Atorvastatin e ke akepaʻa, aʻo kahi hapa liʻiliʻi wale nō o ka rosuvastatin i hana ʻia e ke ake. No laila, ʻoi aku ka maʻalahi o ka atorvastatin i nā pilina lāʻau i hana ʻia e nā enzyme lāʻau lapaʻau ate;

4. ʻOi aku paha nā hopena ʻino o ka ate ma mua o ka rosuvastatin. Ke hoʻohālikelike ʻia me ka atorvastatin, ʻoi aku ka nui o ka hopena o ka rosuvastatin i loko o nā puʻupaʻa. I ka pōkole, ʻo ka atorvastatin a me ka rosuvastatin nā lāʻau hoʻohaʻahaʻa lipid statin ikaika, a aia paha nā ʻokoʻa i ka metabolism o ka lāʻau lapaʻau, ka pilina o ka lāʻau, a me nā hopena ʻino.